NeoSome's In Vitro Expertise: Accelerating Drug Discovery with Precision

In the fast-paced world of drug discovery, the right tools and expertise are critical for moving a program forward. At NeoSome Life Sciences, we understand this need for speed and accuracy. Our in-house in vitro capabilities provide comprehensive support, from early-stage screening to in-depth mechanistic studies. By combining advanced platforms with our scientific expertise in data analysis, we provide you with the insights needed to make crucial decisions.

Our In Vitro Toolkit

We've invested in a robust suite of technologies to support a wide range of research applications. Each platform is chosen for its ability to generate high-quality, reproducible data, ensuring confidence in your results.

Flow Cytometry: Unlocking Cellular Secrets 🧬

Flow cytometry is a powerful technique for analyzing individual cells in a fluid stream. This technology allows us to rapidly quantify and characterize different cell populations based on their size, granularity, and specific surface or intracellular markers. It’s an indispensable tool for:

• Immunophenotyping: Identifying and counting different immune cell types, like T cells and B cells.

• Cell Viability and Apoptosis Assays: Assessing cell health and programmed cell death.

• Intracellular Staining: Analyzing protein expression and signaling pathways within the cell.

This high-throughput method provides a detailed, multi-parameter view of cellular responses, which is essential for understanding drug mechanisms and safety profiles.

ELISA & MSD: The Gold Standard for Protein Analysis

When it comes to quantifying proteins like cytokines, hormones, or biomarkers, ELISA (Enzyme-Linked Immunosorbent Assay) and MSD (Meso Scale Discovery) are our go-to methods.

• ELISA is a classic immunoassay known for its high sensitivity and specificity. It's perfect for single-analyte detection and is a cornerstone of our protein quantification services.

• MSD takes protein detection to the next level. Using electrochemiluminescence, MSD offers several advantages over traditional ELISA, including higher sensitivity, a wider dynamic range, and the ability to multiplex up to 10 analytes from a single, small sample. This saves precious sample volume and provides a more holistic view of complex biological processes.

Both platforms are essential for a variety of applications, from biomarker profiling to pharmacokinetic (PK) studies.

Cell-Based Assays: The Power of Context

In addition to our platform-specific services, we offer a wide variety of cell-based assays. These assays bridge the gap between simple biochemical tests and complex in vivo studies, providing a more physiologically relevant context for your research. We can help you:

• Evaluate compound cytotoxicity and cell proliferation.

• Study receptor-ligand interactions and signal transduction pathways.

• Perform neutralization assays to screen for immune responses.

We work with you to design and customize assays that are perfectly tailored to your research program, ensuring the data you get is relevant and actionable.

And don’t forget our host of Infectious Disease in vitro assays (MICs, MBCs, time kill, PAE)  with a full library of ESCAPE pathogens and Fungal isolates.

More Than Just Data: The NeoSome Difference in Data Analysis

Gathering data is only half the battle. The true value lies in its interpretation. At NeoSome Life Sciences, we don’t just deliver a list of numbers; we provide results. Our team of experienced scientists and study directors takes pride in their ability to perform thorough data analysis, interpretation, and provide meaningful recommendations.

We work closely with our clients to understand their research goals, ensuring that every assay is designed to address pivotal questions. Our data analysis services include:

• Statistical analysis of raw data to identify significant trends and relationships.

• Graphical representation of results for clear and concise reporting.

• Interpretation of findings in the context of your broader research program.

This consultative approach, combined with our in-house capabilities, allows us to provide a seamless workflow from study design to final report, helping you navigate research challenges and achieve your milestones.

Not only do we run assays, we can develop custom assays to fit you research program.  Give us a call to find out how we can help.

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